Principal Investigator / Doctoral Supervisor
Research Group Leader of Stem Cells and Mechanobiology
Email：py.wang@ojlab.ac.cn
Dr Peng-Yuan Wang, Distinguished Principal Investigator of Oujiang Laboratory. He has received several prestigious awards, including the ARC DECRA Fellowship,the VESKI Fellowship, the China Overseas High-level Talents, and the Zhejiang Overseas High-level Talents. He was a PI at Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), and the Director of Shenzhen Key Laboratory of Biomimetic Materials and Cellular Immune Regulation. He has received many awards, such as Vice-Chancellor's Award of Swinburne University, and the representative of China-Australia young scientists.
Dr Wang’s group has developed a variety of bioengineering tools and methods to study the regulation of unique biomechanotransduction signaling. Mammalian cells attach to the extracellular matrix (ECM), where the surfaces control cell adhesion, cytoskeleton, and nucleus. Then, these changes regulate cell behavior, transcriptome profile, and epigenetic state. The research has important significance and potential application in organ development and materiobiology, and the outcomes play a guiding role in designing new biomaterials and cell therapy approaches.
Dr Wang’s group has published more than 100 SCI papers, with over 70 being the first/corresponding authors, including Adv Funct Mater (2), ACS Nano (2), Small (3), Mol Ther (2), ACS Appl Mater Inter (8), Acta Biomater (5), etc. He holds 8 granted invention patents.
(1) Stem Cells and Materials Biology
Our team utilizes extracellular matrix materials to stimulate the directed differentiation or cellular reprogramming of stem cells. Through the biomechanical signaling induced by material surfaces, we regulate cell adhesion, growth, transcriptome profiles, and epigenetic states. This not only holds significant potential applications in biomedical engineering but also provides guidance in the design of biomaterials.
(2) Biomaterials and Tissue Engineering
Our team utilizes methods such as etching, template imprinting, and hydrogels to fabricate various bioengineering materials. We study the behavior patterns of cell growth in 2D and 3D, aiming to uncover the interaction mechanisms between cells and materials, as well as cell-to-cell interactions. Ultimately, we seek to optimize the microenvironment for cell phenotype and tissue development conditions.
The team, led by Dr. Wang Pengyuan as the academic laeder, comprises 2 associate researchers, 2 postdoctoral fellows, and 12 master's and doctoral research students. Additionally, there are 8 research assistants. With an average age of 25, the team is youthful, dynamic, and characterized by vitality and creativity.
Over the past decade, our team has been dedicated to the field of materials biology, accumulating rich achievements and experience in areas such as bioengineering materials, directed differentiation of stem cells, and cell reprogramming. To date, we have published over 80 academic papers in renowned international journals, including sub-journals of Nature and Cell. Since the establishment of the team upon Dr. Wang Pengyuan's return to China in 2018, we have successfully secured funding for 2 national key R&D programs, 1 national natural science fundation (NSFC) project, 2 international cooperation projects with the Chinese Academy of Sciences, 1 provincial-level international cooperation project, and 1 key laboratory project at the municipal level, totaling over 20 million RMB in approved funding.
One notable achievement of the team is the development of the "Drug Screening Technology based on Circulating Tumor Cell Organoids," which received the Second Prize in the Biological category of the 2020 China Shenzhen Innovation and Entrepreneurship Competition (Shenzhen Innovation Competition), earning a certificate from the Shenzhen Municipal Science and Technology Innovation Commission. The following year, the team once again secured the Second Prize in the Growing Group of the Shenzhen Innovation Competition, and was recommended to participate in the China Innovation and Entrepreneurship Competition (National Competition), achieving the sixth place nationally and receiving unanimous recognition from experts in the field.
Looking ahead, the team will continue to delve into the fundamental research and industrial applications of bioengineering materials in the field of stem cells. Our focus is on addressing key scientific and technological challenges in the clinical application of bio materials and cell therapy, unraveling underlying scientific questions, and striving to produce high-quality cells. Additionally, we aim to develop bioengineering materials that are irreplaceable, pioneering the future of biomaterials and cell technology.
Recruitment Announcement: Associate Researchers/Postdoctoral Fellows/Research Assistants – Stem Cells and Engineering Biology
I. Associate Researchers/Postdoctoral Fellows (2-3 positions)
1. Discipline: Biology, Materials, Chemistry.
2. First authorship in more than 2 SCI papers.
3. Experience in project proposal submission.
4. Proficiency in English (priority given to applicants with English proficiency certificates).
5. Positive character, diligent and proactive, optimistic and focused on future goals.
6. Additional bonus materials.
II. Research Assistants (1-2 positions)
1. Discipline: Biology, Materials, Chemistry, Polymer, Chemical Engineering.
2. First authorship in more than 1 SCI paper.
3. Familiarity with biological or material-related techniques, including cell or microbial culture, molecular biology experiments (such as immunofluorescence staining and real-time PCR), advanced nano-material preparation, hydrogels, etc.
4. Assistance in internal affairs of the research group.
5. Proficiency in English (priority given to applicants with English proficiency certificates).
6. Positive character, diligent and proactive, optimistic and focused on future goals.
7. Additional bonus materials.
III. Compensation and Benefits
Associate Researchers: Annual salary > 300,000 RMB + year-end research performance bonus, talent housing provided.
Research Assistants: Annual salary > 250,000 RMB + year-end research performance bonus, talent housing provided.
Postdoctoral Fellow A: Annual salary > 350,000 RMB + year-end research performance bonus, talent housing provided.
Postdoctoral Fellow B: Annual salary > 300,000 RMB + year-end research performance bonus, talent housing provided.
Research Assistants: Annual salary > 150,000 RMB, talent housing provided, enjoying unit-provided benefits.
All positions follow the salary standards of Oujiang Laboratory and comply with relevant policies of Zhejiang Province/Wenzhou City.
Depending on experience and title, candidates may be eligible for employment under Wenzhou City's public institution system, receive relocation subsidies, housing subsidies, transitional housing, etc. Under permissible conditions, joint training with universities in Australia, California (USA), Shanghai, Shenzhen, and other locations is possible.
1. Interested candidates are invited to submit a detailed personal resume (in both Chinese and English) via email, including a list of representative academic achievements such as papers, patents, conference presentations, and details of projects hosted/participated in.
2. Please use the following email format for submission: Send an email to py.wang@ojlab.ac.cn with the subject line indicating "Position + Your Name." The personal resume will be rigorously screened, and interviews will be promptly arranged (via Tencent Meeting) for qualified candidates. Those who do not pass the screening will not receive further notification.
3. Personal information will be treated with strict confidentiality. Highlight your outstanding academic achievements and qualities in your application.
official account
Contact Address：中国浙江省温州市龙湾区永中街道金石路999号
Zip Code：325000
Email：zh@ojlab.ac.cn
