Research interests:

1) Development of multi-modal Patch-seq techniques for eye-brain analysis

2) Non-invasive magnetogenetic neural modulation

3) Neural circuits underlying gender differences in stress

4) Neurobiological mechanisms of neurological/psychiatric diseasesGrant:

Work experience:

since 2023.03, Oujiang Laboratory, Researcher

2021.12-2023.03, Baylor College of Medicine, Assistant Professor

2020.07-2021.12, Texas A&M University, Research Scientist

2019.05-2020.07, The State University of New York at Buffalo, Research Scientist

2016.05-2019.05, The State University of New York at Buffalo, Postdoc

2014.01-2016.05, Children’s Hospital of Chongqing Medical University/China, Postdoc

2013.07-2014.01, Children’s Hospital of Chongqing Medical University/China, Assistant Researcher

1) Neurobiological mechanisms of autism;

2) Neurocircuitry studies of stress;

3) The role of novel non-invasive neurostimulation techniques in the modulation of neurological/psychiatric disorders;

4) Application of Patch-seq technology to parse the brain and expand its application in neurological/psychiatric disorders.

Our research group focuses on the forefront of neuroscience, delving deeply into the study of neurodevelopmental disorders (Autism Spectrum Disorder, ASD and schizophrenia), neurodegenerative diseases (Alzheimer's Disease, AD), stress, addiction, and other neurological/psychiatric disorders. We specifically investigate the associated brain regions/neural circuits, ion channelopathies, and synaptic plasticity mechanisms. Additionally, we explore the genetic and environmental risk factors, as well as gene-environment interactions in neurological/psychiatric disorders.

Furthermore, we aim to explore the mechanisms of novel non-invasive neural stimulation techniques, such as repetitive transcranial magnetic stimulation (rTMS), for the intervention and regulation of neurological/psychiatric disorders.

Our goal is to identify the pathogenic genes, molecular targets, and specific neural circuits involved in these disorders to achieve targeted intervention and regulation.

Our research methodologies include the construction of transgenic animal models, patch-clamp electrophysiology (single-cell/brain slice patch-clamp, multi-channel patch-clamp, Patch-seq, in vivo multi-channel recordings in freely moving small animals, two-photon imaging, neural circuit tracing and whole-brain imaging, chemogenetic/optogenetic neural modulation, rTMS, behavioral assays, and molecular biology techniques (single-cell transcriptomics, PCR, Western Blotting, immunohistochemistry), among others.

Under Dr. Tao Tan's supervision, TanLab at Oujiang Laboratory currently consists of 21 team members: 2 PIs/Co-PIs, 2 postdoctoral researchers, 4 research assistants (2 assistant researchers and 2 research assistants), and 10 graduate students. Our team members are young, energetic passionate, full of vitality and creativity.

Long-term Recruitment of Outstanding Talents in Neurobiology and Related Fields

Our team is seeking exceptional candidates in neurobiology and related fields for positions including Associate Researchers, Assistant Researchers, Postdoctoral Fellows, and Research Assistants. We also welcome undergraduate and graduate students in relevant fields to conduct collaborative research, or internships in our laboratory.

I. Associate Researcher

1. Ph.D. in neurobiology, biomedical engineering, basic medicine, molecular biology, pharmacology, or related fields; with 1-2 rounds of postdoctoral training experience domestically or internationally.

2. Within the past 3 years, published at least 2 high-level research papers as first author in related fields, including at least 1 paper in a Chinese Academy of Sciences Q1 journal.

3. Expertise in specific techniques such as patch-clamp, in vivo multi-channel, fiber photometry, mini-scope single-cell calcium imaging, single-cell RNA-sequencing, two-photon imaging, etc.

4. Able to independently conduct and guide students in related experiments.

5. Experience in grant applications, have been funded by national or provincial projects.

II. Postdoctoral Fellows and Assistant Researcher

1. Ph.D. in neurobiology, biomedical engineering, basic medicine, molecular biology, pharmacology, or related fields.

2. Strong academic ethics and collaborative, with good communication skills and ability to solve problems independently.

3. Expertise in specific techniques such as patch-clamp, in vivo multi-channel, fiber photometry, mini-scope single-cell calcium imaging, single-cell RNA-sequencing, two-photon imaging, etc.

4. Within the past 3 years, published high-level research papers as first author (or co-first author) in related fields, able to clearly express ideas and thoughts.

III. Research Assistant

1. Master's degree with background in neurobiology, biomedical engineering, biology, medicine, or related fields.

2. Research experience in patch-clamp, in vivo multi-channel, fiber photometry, mini-scope single-cell calcium imaging, single-cell RNA-sequencing, two-photon imaging; basic programming skills in Matlab, Python;

IV. Interns and Volunteers

1. Sophomore or above in neurobiology, biomedical engineering, basic medicine, or related majors.

2. Strong interest in brain science.

Location: Wenzhou, Zhejiang

Benefits

- Competitive salary and research conditions.

- Fully supportive and customized care development plans.

- Formal contract with social security. Additional benefits include paid leave, apartments, free physical examinations, and other benefits.

- Assistance with children's school enrollment.

Applicants should send their CV (with representative publications) and other materials to tantao@ojlab.ac.cn. Postdoctoral and Assistant Researcher applicants need to provide at least two recommendation letters. After receiving and preliminarily reviewing the materials, the research group will contact applicants for further communication.